PRMT2 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP1003a
Catalog Number: AC-AP1003a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB0191
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB0191
Applications: WB
Datasheet
Request Information
Background:
Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.
Other Names:
Protein arginine N-methyltransferase 2, 211-, Histone-arginine N-methyltransferase PRMT2, PRMT2, HMT1, HRMT1L1
Target/Specificity:
This PRMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-375 amino acids from the C-terminal region of human PRMT2.
Antigen Region:
344-375
Antigen Type: Synthetic Peptide
Gene Name: PRMT2
Gene ID: 3275
Primary Accession: P55345
NCBI Accession: NP_001229793.1;NP_001229794.1;NP_001526.2;NP_996845.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.
Other Names:
Protein arginine N-methyltransferase 2, 211-, Histone-arginine N-methyltransferase PRMT2, PRMT2, HMT1, HRMT1L1
Target/Specificity:
This PRMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-375 amino acids from the C-terminal region of human PRMT2.
Antigen Region:
344-375
Antigen Type: Synthetic Peptide
Gene Name: PRMT2
Gene ID: 3275
Primary Accession: P55345
NCBI Accession: NP_001229793.1;NP_001229794.1;NP_001526.2;NP_996845.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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