PRMT3 polyclonal (N-term), anti-human
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In stock
SKU
AC-AP1004a
Catalog Number: AC-AP1004a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB0029
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB0029
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.
Other Names:
Protein arginine N-methyltransferase 3, 211-, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3, PRMT3, HRMT1L3
Target/Specificity:
This PRMT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-173 amino acids from the N-terminal region of human PRMT3.
Antigen Region:
142-173
Antigen Type: Synthetic Peptide
Gene Name: PRMT3 (HGNC:30163)
Gene ID: 10196
Primary Accession: O60678
NCBI Accession: NP_005779.1
Other Accession: Q922H1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.
Other Names:
Protein arginine N-methyltransferase 3, 211-, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3, PRMT3, HRMT1L3
Target/Specificity:
This PRMT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-173 amino acids from the N-terminal region of human PRMT3.
Antigen Region:
142-173
Antigen Type: Synthetic Peptide
Gene Name: PRMT3 (HGNC:30163)
Gene ID: 10196
Primary Accession: O60678
NCBI Accession: NP_005779.1
Other Accession: Q922H1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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