PRMT5 Polyclonal Antibody

Background:
This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
HRMT1L5, IBP72, JBP1, SKB1, SKB1Hs, PRMT5

Immunogen: A synthetic peptide of human PRMT5 (NP_006100.2).

Swissprot: O14744
Gene ID: 10419

Calculated MW: 53 kDa/66 kDa/67 kDa/71 kDa/72 kDa
Observed MW: 73 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.