PRMT6 (clone 2C3-F1-G1), anti-human antibody
€295.00
In stock
SKU
AC-ABV12041-100
Catalog Number: AC-ABV12041-100
Size: 100 µg
Host: Human IgG
Applications: WB, IHC, IF
Datasheet
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Size: 100 µg
Host: Human IgG
Applications: WB, IHC, IF
Datasheet
Request Information
Background:
PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes. IPRMT6 is functionally distinct from two previously characterized type I enzymes, PRMT1 and PRMT4. In addition, PRMT6 displays automethylation activity, it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication.
Other Names:
HRMT1L6
Primary Accession: Q96LA8
Gene Name: PRMT6
Gene ID: 55170
PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes. IPRMT6 is functionally distinct from two previously characterized type I enzymes, PRMT1 and PRMT4. In addition, PRMT6 displays automethylation activity, it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication.
Other Names:
HRMT1L6
Primary Accession: Q96LA8
Gene Name: PRMT6
Gene ID: 55170
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