PRMT6 (clone 2C3-F1-G1), anti-human

Background:
PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes.
IPRMT6 is functionally distinct from two previously characterized type I enzymes, PRMT1 and PRMT4. In addition, PRMT6 displays automethylation activity; it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication.

Synonyms: PRMT6

Cellular Location: Nucleus

Immunogen:
Purified recombinant human PRMT6 protein fragments expressed in E.coli.

Gene Symbol: PRMT6

Gene ID: 55170

Swiss prot: Q96LA8

Calculated MW: 42kDa

Recommended dilution:
WB 1:1000, IHC 1:300

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.