PRMT6 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP1009a
Catalog Number: AC-AP1009a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7367
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7367
Applications: WB
Datasheet
Request Information
Background:
Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.
Other Names:
Protein arginine N-methyltransferase 6, 211-, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6, Histone-arginine N-methyltransferase PRMT6, PRMT6, HRMT1L6
Target/Specificity:
This PRMT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of human PRMT6.
Antigen Region:
19-48
Antigen Type: Synthetic Peptide
Gene Name: PRMT6
Gene ID: 55170
Primary Accession: Q96LA8
NCBI Accession: NP_060607.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.
Other Names:
Protein arginine N-methyltransferase 6, 211-, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6, Histone-arginine N-methyltransferase PRMT6, PRMT6, HRMT1L6
Target/Specificity:
This PRMT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of human PRMT6.
Antigen Region:
19-48
Antigen Type: Synthetic Peptide
Gene Name: PRMT6
Gene ID: 55170
Primary Accession: Q96LA8
NCBI Accession: NP_060607.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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