PROC Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP13543c
Background:
This gene encodes a vitamin K-dependent plasmaglycoprotein. The encoded protein is cleaved to its activated formby the thrombin-thrombomodulin complex. This activated formcontains a serine protease domain and functions in degradation ofthe activated forms of coagulation factors V and VIII. Mutations inthis gene have been associated with thrombophilia due to protein Cdeficiency, neonatal purpura fulminans, and recurrent venousthrombosis.
Other Names:
Vitamin K-dependent protein C, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, Vitamin K-dependent protein C light chain, Vitamin K-dependent protein C heavy chain, Activation peptide, PROC
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13543c was selected from the Center region of PROC. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PROC
Gene ID: 5624
Primary Accession: P04070
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a vitamin K-dependent plasmaglycoprotein. The encoded protein is cleaved to its activated formby the thrombin-thrombomodulin complex. This activated formcontains a serine protease domain and functions in degradation ofthe activated forms of coagulation factors V and VIII. Mutations inthis gene have been associated with thrombophilia due to protein Cdeficiency, neonatal purpura fulminans, and recurrent venousthrombosis.
Other Names:
Vitamin K-dependent protein C, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, Vitamin K-dependent protein C light chain, Vitamin K-dependent protein C heavy chain, Activation peptide, PROC
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13543c was selected from the Center region of PROC. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PROC
Gene ID: 5624
Primary Accession: P04070
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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