PROC Polyclonal Antibody

Background:
This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009]

Research Area: Cardiovascular

Synonyms:
Activation peptide, Anticoagulant protein C, APC, Autoprothrombin IIA, Blood coagulation factor XIV, EC 3.4.21.69, PC, proC, PROC, PROC1, Protein C (inactivator of coagulation factors Va and VIIIa), THPH3, THPH4, Vitamin K dependent protein C

Immunogen: Synthetic peptide of human PROC

Swissprot: P04070
Gene Accession: NP000303

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 3 mg/mL
Dilution: IHC 1:100-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.