Procalcitonin human active recombinant protein

Protein Family: Hormones

Pathway and Disease: Endocrine System

Alternate Names: Procalcitonin, PCT, CALC1, Calcitonin precursor, Calcitonin preproproteinDescription:
Procalcitonin is a peptide hormone mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, an N terminal residue, calcitonin and katacalcin. Levels of unprocessed procalcitonin rise significantly after bacterial infection, trauma or shock. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of these ions in bone. Recombinant procalcitonin comprises a 114 amino acid fragment (3-116) corresponding to the unprocessed procalcitonin protein and is expressed in E. coli with an amino-terminal hexahistidine

Source: E. coli

Applications: E, WB

Accession No.: P01258

MW: 17.34 kDa

Sequence:
His-Tag sequence not included: FRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSSLDSPRSKRCGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAPGKKRDMSSDLERDHRPHVSMPQNAN

Purity:
Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA.

Format:
Each vial contains 0.01 mg protein (liquid) in PBS pH7.4, 50% glycerol. Final concentration 0.1-1 mg/ml.

Storage: Store at -20°C. Product is guaranteed one year from the date of shipment.