Profilin1 PFN1 monoclonal, anti-human, mouse, rat

Description: Anti-Profilin1 PFN1 Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Protein Function:
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR..

Other Names: Profilin-1, Epididymis tissue protein Li 184a, Profilin I, PFN1

Clone Name(s):
Clone: ABCD-16

Subcellular Localization: Cytoplasm, cytoskeleton.

Tissue Specificity: Expressed in epididymis (at protein level)..

Gene ID: 5216

Immunogen: A synthesized peptide derived from human Profilin1

Calculated MW: 15054

Purification: Affinity-chromatography

Format: Liquid

Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.