Progesterone (clone EBS-O-048), anti-all species

Source:
A BALB/c mouse was immunized with Progesterone-11a-hemisuccinate conjugated to BSA (Progesterone-11a-HMS-BSA).
Fusion partner: X63-Ag8-653.

Specifications:
EBS-O-048 is specific for progesterone. It exhibits minimal cross reactivity with related compounds in ELISA. Progesterone is a steroid hormone synthesized from the cholesterol derivative, pregnenolone, in the cortex of the adrenal gland. Progesterone is secreted by the corpus luteum and acts to prepare the endometrium for the implantation of a fertilized egg. During pregnancy, it is secreted by the placenta to prevent spontaneous abortion and to stimulate the development of mammary tissue to produce milk. Thus, progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy. Luteinized theca cells of normal ovary secrete progesterone.

Species reactivity:
Positive: All species.

Applications:
Determination of progesterone levels.
ELISA: +

Positive control: Ovary or placenta.

References:
- Fantl, V.E, et al, J. Steroid Biochem.17: 125-130 (1982).
- Sharma, I. Refinement of analytical technologies for detection of biomolecules of importance to the dairy sector.PhD Thesis Massey University (2011)