Prohibitin polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
PHB(Prohibitin), also known as PHB1, is a protein that in humans is encoded by the PHB gene. The human prohibitin gene family consists of 1 functional PHB gene on 17q21 and 4 processed pseudogenes, each on a different chromosome. The Phbgene has also been described in animals, fungi, plants, and unicellular eukaryotes. Expressed in blood vessels of human white fat, the work suggested the development of targeted drugs for treatment of obese patients. Prohibitins are divided in two classes, termed Type-I and Type-II prohibitins, based on their similarity to yeast PHB1 and PHB2, respectively. Each organism has at least one copy of each type of prohibitin gene. Prohibitins may have multiple functions including: Mitochondrial function and morphology, Transcriptional modulation.

Description:
Rabbit IgG polyclonal antibody for Prohibitin (PHB) detection. Tested with WB, IHC-P, ICC in Human, Mouse, Rat.

Synonyms:
PHB antibody, PHB_HUMAN antibody, PHB1 antibody, prohibitin antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminal of human Prohibitin, identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Reactivity: human, mouse, rat. No cross reactivity with other proteins.

Applications: WB, IHC-P, ICC

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.