PROK1 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60468
Background:
Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) induces proliferation,migration and fenestration in capillary endothelialcells derived from endocrine glands. EG-VEGF possesses a HIF-1 binding site; its expression isinduced by hypoxia and restricted to the steroidogenic glands(ovary,testis, adrenal and placenta). EG-VEGF expression is often complementary to the expression of VEGF,suggesting that these moleculesfunction in a coordinatedmanner. EG-VEGFis an example of a class of highly specificmitogensthat act to regulate proliferation and differentiation of the vascular endothelium in a tissue-specific manner. EG-VEGFis expressed largely in one type of tissue and actsselectively on one type of endothelium. EG-VEGF, possiblythrough binding to a G protein-coupled receptor, resultsin the activation ofMAPK p44/42 and phosphatidylinositol 3-kinase signaling pathways, leading to proliferation,migration and survival of responsive endothelialcells.
Alternative Name:
Prokineticin-1, Endocrine-gland-derived vascular endothelial growth factor, EG-VEGF, Mambakine, PROK1, UNQ600/PRO1186
Application Dilution: WB: 1:500~1:1000
Specificity: PROK1 polyclonal antibody detects endogenous levels of PROK1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human PROK1.
MW: ~ 12 kDa
Swis Prot.: P58294
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) induces proliferation,migration and fenestration in capillary endothelialcells derived from endocrine glands. EG-VEGF possesses a HIF-1 binding site; its expression isinduced by hypoxia and restricted to the steroidogenic glands(ovary,testis, adrenal and placenta). EG-VEGF expression is often complementary to the expression of VEGF,suggesting that these moleculesfunction in a coordinatedmanner. EG-VEGFis an example of a class of highly specificmitogensthat act to regulate proliferation and differentiation of the vascular endothelium in a tissue-specific manner. EG-VEGFis expressed largely in one type of tissue and actsselectively on one type of endothelium. EG-VEGF, possiblythrough binding to a G protein-coupled receptor, resultsin the activation ofMAPK p44/42 and phosphatidylinositol 3-kinase signaling pathways, leading to proliferation,migration and survival of responsive endothelialcells.
Alternative Name:
Prokineticin-1, Endocrine-gland-derived vascular endothelial growth factor, EG-VEGF, Mambakine, PROK1, UNQ600/PRO1186
Application Dilution: WB: 1:500~1:1000
Specificity: PROK1 polyclonal antibody detects endogenous levels of PROK1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human PROK1.
MW: ~ 12 kDa
Swis Prot.: P58294
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review