PROK2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8369
Background:
Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the suprachiasmatic nucleus (SCN) with receptors located in the critical autonomic control centers of the brain. It has a depolarizing effect on neurons expressing the receptor. PK2 is predominantly controlled by the endogenous circadian clock, but light also plays a modulatory role. PK2 functions as a critical SCN output molecule responsible for circadian locomotor rhythms. PK2 expression is high during the day, and responsive to nocturnal light pulses. PK2 also functions as a chemoattractant for subventricular zone-derived neuronal progenitors.
Alternative Name:
Prokineticin-2, PK2, Protein Bv8 homolog, PROK2, BV8
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: PROK2 polyclonal antibody detects endogenous levels of PROK2 protein.
Immunogen:
Recombinant full length Human PROK2.
MW: ~ 14 kDa
Swis Prot.: Q9HC23
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the suprachiasmatic nucleus (SCN) with receptors located in the critical autonomic control centers of the brain. It has a depolarizing effect on neurons expressing the receptor. PK2 is predominantly controlled by the endogenous circadian clock, but light also plays a modulatory role. PK2 functions as a critical SCN output molecule responsible for circadian locomotor rhythms. PK2 expression is high during the day, and responsive to nocturnal light pulses. PK2 also functions as a chemoattractant for subventricular zone-derived neuronal progenitors.
Alternative Name:
Prokineticin-2, PK2, Protein Bv8 homolog, PROK2, BV8
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: PROK2 polyclonal antibody detects endogenous levels of PROK2 protein.
Immunogen:
Recombinant full length Human PROK2.
MW: ~ 14 kDa
Swis Prot.: Q9HC23
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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