PROKR1 Polyclonal Antibody

Background:
This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage.PROKR1 (Prokineticin Receptor 1) is a Protein Coding gene. Diseases associated with PROKR1 include Ectopic Pregnancy. Among its related pathways are Peptide ligand-binding receptors and RET signaling. GO annotations related to this gene include G-protein coupled receptor activity and neuropeptide Y receptor activity. An important paralog of this gene is PROKR2.

Research Area: Neuroscience, Signal Transduction

Synonyms:
EG-VEGF receptor, G protein coupled receptor 73, G protein coupled receptor ZAQ, G-protein coupled receptor 73, G-protein coupled receptor ZAQ, GPR73, GPR73a, PK R1, PK-R1, PKR1, PKR1, Prokineticin receptor 1, PROKR1, zaq

Immunogen: Synthetic peptide of human PROKR1

Swissprot: Q8TCW9
Gene Accession: NP620414

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.14 mg/mL
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.