PROM1 Blocking Peptide (Center)
€363.00
In stock
SKU
AC-BP21276c
Background:
May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol- containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).
Other Names:
Prominin-1, Antigen AC133, Prominin-like protein 1, CD133, PROM1, PROML1
Target/Specificity:
The synthetic peptide sequence is selected from aa 361-375 of HUMAN PROM1
Gene Name: PROM1
Gene ID: 8842
Primary Accession: O43490
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol- containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).
Other Names:
Prominin-1, Antigen AC133, Prominin-like protein 1, CD133, PROM1, PROML1
Target/Specificity:
The synthetic peptide sequence is selected from aa 361-375 of HUMAN PROM1
Gene Name: PROM1
Gene ID: 8842
Primary Accession: O43490
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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