PROM1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: AC133, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4

Cellular Location: Apical cell membrane Cell projection Endoplasmic reticulum Endoplasmic reticulum-Golgi intermediate compartment Multi-pass membrane protein cilium microvillus membrane photoreceptor outer segment

Immunogen:
A synthetic peptide of human PROM1

Gene Symbol: PROM1

Gene ID: 8842

Swiss prot: O43490

Calculated MW: 97kDa

Recommended dilution:
WB 1:1000-3000, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.