Prominin-1 (clone 8F2-H6-D6), anti-human

Background:
This gene encodes a pentaspan transmembrane glycoprotein.The protein localizes to membrane protrusions and is often expressed on adult stem cells,where it is thought to function in maintaining stem cell properties by suppressing differentiation.Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease.Expression of this gene is also associated with several types of cancer.This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner.Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq,Mar 2009]

Synonyms: AC133, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4

Cellular Location: Apical cell membrane Cell projection Endoplasmic reticulum Endoplasmic reticulum-Golgi intermediate compartment Multi-pass membrane protein cilium microvillus membrane photoreceptor outer segment

Immunogen:
Purified recombinant human Prominin-1 protein fragments expressed in E.coli.

Gene Symbol: Prominin-1

Gene ID: 8842

Swiss prot: O43490

Calculated MW: 133kDa

Recommended dilution:
WB 1:3000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.