Propoxyphene polyclonal, anti-human, mouse, rat
€798.00
In stock
SKU
252444
Protein Family: Biochemicals
Pathway and Disease: Nervous and Sensory Systems, Signaling Molecules and Interaction
Description:
Norpropoxyphene, a major metabolite of the opioid analgesic drug dextropropoxyphene, is responsible for many of the side effects associated with use of this drug, especially the unusual toxicity seen during dextropropoxyphene overdose. Norpropoxyphene is a potent pro-convulsant and blocker of sodium and potassium channels, particularly in heart tissue, which produces prolonged intracardiac conduction time and can lead to heart failure following even minor overdoses. The toxicity of norpropoxyphene makes dextropropoxyphene up to 10 times more likely to cause death following overdose compared to other opioid analgesics, and has led to the removal of dextropropoxyphene from the market in some countries.
Alternate Names: Propoxyphene, Norpropoxyphene
Application Notes: E: 1:10,000-1:50,000; WB: 1:200-1:1,000
Accession No.: 3376-94-1
Antigen: Propoxyphene-BSA
Format: Each vial contains 0.1 ml IgG (7-12 mg/ml) in 20mM phosphate, 150mM NaCl buffer, pH7.2 with 0.09% sodium azide. Antibody was purified by caprylic acid and ammonium sulfate precipitation.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Nervous and Sensory Systems, Signaling Molecules and Interaction
Description:
Norpropoxyphene, a major metabolite of the opioid analgesic drug dextropropoxyphene, is responsible for many of the side effects associated with use of this drug, especially the unusual toxicity seen during dextropropoxyphene overdose. Norpropoxyphene is a potent pro-convulsant and blocker of sodium and potassium channels, particularly in heart tissue, which produces prolonged intracardiac conduction time and can lead to heart failure following even minor overdoses. The toxicity of norpropoxyphene makes dextropropoxyphene up to 10 times more likely to cause death following overdose compared to other opioid analgesics, and has led to the removal of dextropropoxyphene from the market in some countries.
Alternate Names: Propoxyphene, Norpropoxyphene
Application Notes: E: 1:10,000-1:50,000; WB: 1:200-1:1,000
Accession No.: 3376-94-1
Antigen: Propoxyphene-BSA
Format: Each vial contains 0.1 ml IgG (7-12 mg/ml) in 20mM phosphate, 150mM NaCl buffer, pH7.2 with 0.09% sodium azide. Antibody was purified by caprylic acid and ammonium sulfate precipitation.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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