Proteinase Inhibitor 9 (PI9) polyclonal, anti-human antibody
€275.00
In stock
SKU
AC-ABV10400-100
Catalog Number: AC-ABV10400-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
Proteinase inhibitor 9 (PI-9, also designated cytoplasmic antiproteinase 3, or CAP3) is a 42 kDa member of the ovalbumin family of serpins that is expressed in placenta, lung and cytotoxic lymphocytes. PI-9 is a potent inhibitor of granzyme B and of granzyme B-mediated apoptosis, and is also an inhibitor of capase-1 and, to a smaller extent, caspase-4 and caspase-8. PI-9 expression is also upregulated in response to inflammatory stimuli. This upregulation protects cells from apoptosis induced by endogenously expressed or released granzyme B, particulary during target cell killing
Other Names:
CAP3 , CAP 3 , Cytoplasmic antiase3 PI9 , Protease inhibitor9 ovalbumin type Serpin B9 Serine , Cysteine ase Inhibitor
Primary Accession: P50453
Gene Name: SERPINB9
Gene ID: 5272
Concentration (mg/ml): 0.5 mg/ml
Proteinase inhibitor 9 (PI-9, also designated cytoplasmic antiproteinase 3, or CAP3) is a 42 kDa member of the ovalbumin family of serpins that is expressed in placenta, lung and cytotoxic lymphocytes. PI-9 is a potent inhibitor of granzyme B and of granzyme B-mediated apoptosis, and is also an inhibitor of capase-1 and, to a smaller extent, caspase-4 and caspase-8. PI-9 expression is also upregulated in response to inflammatory stimuli. This upregulation protects cells from apoptosis induced by endogenously expressed or released granzyme B, particulary during target cell killing
Other Names:
CAP3 , CAP 3 , Cytoplasmic antiase3 PI9 , Protease inhibitor9 ovalbumin type Serpin B9 Serine , Cysteine ase Inhibitor
Primary Accession: P50453
Gene Name: SERPINB9
Gene ID: 5272
Concentration (mg/ml): 0.5 mg/ml
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