Prothrombin polyclonal, anti-rat

Quantity: 100 µg

Background:
F2(Coagulation Factor II), also known as thrombin, is a serine protease that in humans is encoded by the F2 gene. Royle et al.(1987) assigned the gene for human prothrombin(F2) to chromosome 11p11-q12 by analysis of a panel of somatic cell hybrid DNAs and by in situ hybridization, using both cDNA and genomic probes. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII(F8), and XIII(F13A1). Thrombin also inhibits coagulation by activating protein C.

Description:
Rabbit IgG polyclonal antibody for Prothrombin (F2) detection. Tested with WB in Rat.

Synonyms:
coagulation factor II(thrombin) antibody, Coagulation factor II antibody, Coagulation factor II precursor antibody, Coagulation factor II thrombin antibody, Dysprothrombinemia antibody, EC 3.4.21.5 antibody, F 2 antibody, F2 antibody, Factor II antibody, Hyperprothrombinemia antibody, Hypoprothrombinemia antibody, Prepro coagulation factor II antibody, Prothrombin antibody, Prothrombin B chain antibody, prothrombin B-chain antibody, PT antibody, RPRGL2 antibody, Serine protease antibody, THPH1 antibody, THRB antibody, THRB_HUMAN antibody, Thrombin antibody, Thrombin heavy chain antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of rat Prothrombin(600-612aa THVFRLKRWMQKV).A synthetic peptide corresponding to a sequence at the C-terminus of rat Prothrombin(600-612aa THVFRLKRWMQKV).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.