PRPF3 Polyclonal Antibody

Background:
The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. This gene product is one of several proteins that associate with U4 and U6 snRNPs. Mutations in this gene are associated with retinitis pigmentosa-18.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Neuroscience

Synonyms:
hPrp3, HPRP3P, Pre mRNA splicing factor 3, Pre-mRNA-splicing factor 3, Precursor mRNA-processing factor 3, S. crevisiae, homolog of, PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae), Prp3p, PRPF3, PRPF3, RP18, SNRNP90, U4/U6 small nuclear ribonucleoprotein PRP3, U4/U6 snRNP 90 kDa protein

Immunogen: Fusion protein of human PRPF3

Swissprot: O43395
Gene Accession: BC000184

Calculated MW: 78 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.