PRPF8 polyclonal, anti-human, mouse, rat

Background:
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.

Synonyms: HPRP8, PRP8, PRPC8, RP13, SNRNP220

Cellular Location: Nucleus speckle

Immunogen:
A synthetic peptide of human PRPF8

Gene Symbol: PRPF8

Gene ID: 10594

Swiss prot: Q6P2Q9

Calculated MW: 274kDa

Recommended dilution:
WB 1:500-1000, IHC 1:50-100, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.