PRPF8 Polyclonal Antibody

Background:
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Neuroscience

Synonyms:
PRPF8, HPRP8, PRP8, PRPC8, RP13, SNRNP220, PRPF8

Immunogen: A synthetic peptide of human PRPF8 (NP_006436.3).

Swissprot: Q6P2Q9
Gene ID: 10594

Calculated MW: 273 kDa
Observed MW: 274 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.