PRPS1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms: ARTS, CMTX5, DFN2, DFNX1, PPRibP, PRS-I, PRSI

Cellular Location: Cytosol

Immunogen:
A synthetic peptide of human PRPS1

Gene Symbol: PRPS1

Gene ID: 5631

Swiss prot: P60891

Calculated MW: 35kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.