PRPS1/PRPS2/PRPS3 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP7178a
Background:
Phosphoribosylpyrophosphate synthetase (PRPS) catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for the de novo and salvage pathways of purine, pyrimidine, and pyridine biosynthesis. Defects in PRPS1 are the cause of PRPS-related gout, also known as gout due to PRPS1 superactivity. It is a familial disorder characterized by excessive purine production, gout and uric acid urolithiasis.
Other Names:
Ribose-phosphate pyrophosphokinase 1, PPRibP, Phosphoribosyl pyrophosphate synthase I, PRS-I, PRPS1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7178a was selected from the C-term region of human PRPS1/2/3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PRPS1 (HGNC:9462)
Gene ID: 5631
Primary Accession: P60891
Other Accession: Q5JV75
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Phosphoribosylpyrophosphate synthetase (PRPS) catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for the de novo and salvage pathways of purine, pyrimidine, and pyridine biosynthesis. Defects in PRPS1 are the cause of PRPS-related gout, also known as gout due to PRPS1 superactivity. It is a familial disorder characterized by excessive purine production, gout and uric acid urolithiasis.
Other Names:
Ribose-phosphate pyrophosphokinase 1, PPRibP, Phosphoribosyl pyrophosphate synthase I, PRS-I, PRPS1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7178a was selected from the C-term region of human PRPS1/2/3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PRPS1 (HGNC:9462)
Gene ID: 5631
Primary Accession: P60891
Other Accession: Q5JV75
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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