PRPS1/PRPS2/PRPS3 polyclonal (N-term), anti-human, mouse

PRPS1/PRPS2/PRPS3 polyclonal (N-term), anti-human, mouse

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In stock
SKU
AC-AP7061A
Catalog Number: AC-AP7061A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB5438
Applications: WB
Datasheet

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Background:
Phosphoribosylpyrophosphate synthetase (PRPS; EC 2.7.6.1) catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for the de novo and salvage pathways of purine, pyrimidine, and pyridine biosynthesis. By PCR of human lymphoblast mRNA using primers based on the cDNA sequence of rat PRS I (Prps1), Roessler et al. (1990) isolated a partial human PRPS1 cDNA. They used this partial cDNA to screen lymphoblast cDNA libraries and isolated additional cDNAs corresponding to the entire PRPS1 coding region. The deduced PRPS1 protein has 318 amino acids.

Other Names:
Ribose-phosphate pyrophosphokinase 1, PPRibP, Phosphoribosyl pyrophosphate synthase I, PRS-I, PRPS1

Target/Specificity:
This PRPS1/PRPS2/PRPS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-109 amino acids from the N-terminal region of human PRPS1/PRPS2/PRPS3.

Antigen Region:
79-109

Antigen Type: Synthetic Peptide

Gene Name: PRPS1 (HGNC:9462)
Gene ID: 5631
Primary Accession: P60891
NCBI Accession: NP_001191331.1;NP_002755.1
Other Accession: Q7ZXC9; P09330; Q9CS42; Q4R4R7; P11908; P60892; Q9D7G0; Q4R4U3; Q2HJ58
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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