PRR5 polyclonal, anti-human, mouse, rat
€484.00
In stock
SKU
254461
Protein Family: Enzymes
Pathway and Disease: Signaling Molecules and Interaction
Description:
Proline-rich protein 5 (PRR5), also known as Protor-1, is a 388 amino acid protein in Protor family, is thought to act as a tumor suppressor in breast and colorectal tumorigenesis. PRR5 is widely expressed and possesses two RICTOR interaction sites and a C-terminal Proline rich region. It promotes Rapamycin complex 2 (mTORC2) activity. There are four isoforms of PRR5 that are produced as a result of alternative splicing events and these isoforms play an important role in the modulation of platelet-derived growth factor signaling and in the regulation of PDGFR-beta expression.
Alternate Names: Proline-rich Protein 5, Protor1, Protor-1
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_851850
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human PRR5.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
Proline-rich protein 5 (PRR5), also known as Protor-1, is a 388 amino acid protein in Protor family, is thought to act as a tumor suppressor in breast and colorectal tumorigenesis. PRR5 is widely expressed and possesses two RICTOR interaction sites and a C-terminal Proline rich region. It promotes Rapamycin complex 2 (mTORC2) activity. There are four isoforms of PRR5 that are produced as a result of alternative splicing events and these isoforms play an important role in the modulation of platelet-derived growth factor signaling and in the regulation of PDGFR-beta expression.
Alternate Names: Proline-rich Protein 5, Protor1, Protor-1
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_851850
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human PRR5.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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