PSA (clone ), anti-human

Protein Family: Enzymes, Peptidases

Pathway and Disease: Cancers

Description:
Human prostate-specific antigen (PSA or KLK3) is an important marker for the diagnosis and management of prostate cancer. This is an androgen-regulated glycoprotein of the kallikrein-related protease family secreted by prostatic epithelial cells. Its physiological function is to cleave semenogelins in the seminal coagulum and its enzymatic activity is strongly modulated by zinc ions.

Alternate Names: PSA, Prostate-specific antigen, Kallikrein-3, Semenogelase, Gamma-seminoprotein, Seminin, P-30 antigen, KLK3, APS

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P07288

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human PSA.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.