PSA polyclonal, anti-human, rat

Quantity: 100 µg

Background:
Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. KLK3 is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. This gene is mapped to 19q13.33. KLK3 is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. KLK3 is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving the cervical mucous cap, allowing the entry of sperm. It is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia.

Description:
Rabbit IgG polyclonal antibody for Prostate-specific antigen (KLK3) detection. Tested with WB in Human, Rat.

Synonyms:
antigen, prostate-specific antibody, APS antibody, Gamma seminoprotein antibody, Gamma-seminoprotein antibody, hK3 antibody, Kallikrein 3 antibody, Kallikrein 3, (prostate specific antigen) antibody, Kallikrein related peptidase 3 antibody, Kallikrein-3 antibody, KLK 3 antibody, KLK2A1 antibody, KLK3 antibody, KLK3_HUMAN antibody, P 30 antigen antibody, P-30 antigen antibody, P30 antigen antibody, Prostate Specific Antigen antibody, Prostate-specific antigen antibody, PSA antibody, Semenogelase antibody, Seminin antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human PSA recombinant protein (Position: I25-P261). Human PSA shares 54% amino acid (aa) sequence identity with rat PSA.E.coli-derived human PSA recombinant protein (Position: I25-P261). Human PSA shares 54% amino acid (aa) sequence identity with rat PSA.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.