PSCA Polyclonal Antibody

Background:
PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.

Research Area: Stem Cells

Synonyms:
PRO 232, PRO232, Prostate stem cell antigen

Immunogen: Synthetic peptide of human PSCA

Swissprot: O43653
Gene Accession: Hs.652235

Calculated MW: 13 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.78 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.