PSCD1 antibody (clone 1D6), anti-human
€435.00
In stock
SKU
AC-AT3449a
Catalog Number: AC-AT3449a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, IF, E
Request Information AC-AT3449a">Request Information
Background:
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2.
Other Names:
Cytohesin-1, PH, SEC7 and coiled-coil domain-containing protein 1, SEC7 homolog B2-1, CYTH1, D17S811E, PSCD1
Antigen Type:
Recombinant Protein
Gene Name: CYTH1 (HGNC:9501)
Gene ID: 9267
NCBI Accession: NP_004753.1;NP_059430.2
Primary Accession: Q15438
Other Accession: BC050452
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2.
Other Names:
Cytohesin-1, PH, SEC7 and coiled-coil domain-containing protein 1, SEC7 homolog B2-1, CYTH1, D17S811E, PSCD1
Antigen Type:
Recombinant Protein
Gene Name: CYTH1 (HGNC:9501)
Gene ID: 9267
NCBI Accession: NP_004753.1;NP_059430.2
Primary Accession: Q15438
Other Accession: BC050452
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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