PSCD2 antibody (clone 6H5), anti-human, rat
€435.00
In stock
SKU
AC-AT3450a
Catalog Number: AC-AT3450a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IF, Ehttps://www.abcepta.com/products/pdf_download/AT3450a-PSCD2-Antibody-monoclonal-M02">Request Information AC-AT3450a">Request Information
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IF, Ehttps://www.abcepta.com/products/pdf_download/AT3450a-PSCD2-Antibody-monoclonal-M02">Request Information AC-AT3450a">Request Information
Background:
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
Cytohesin-2, ARF exchange factor, ARF nucleotide-binding site opener, Protein ARNO, PH, SEC7 and coiled-coil domain-containing protein 2, CYTH2, ARNO, PSCD2, PSCD2L
Antigen Type:
Recombinant Protein
Gene Name: CYTH2 (HGNC:9502)
Gene ID: 9266
NCBI Accession: NP_004219.3;NP_059431.1
Primary Accession: Q99418
Other Accession: NM_017457
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
Cytohesin-2, ARF exchange factor, ARF nucleotide-binding site opener, Protein ARNO, PH, SEC7 and coiled-coil domain-containing protein 2, CYTH2, ARNO, PSCD2, PSCD2L
Antigen Type:
Recombinant Protein
Gene Name: CYTH2 (HGNC:9502)
Gene ID: 9266
NCBI Accession: NP_004219.3;NP_059431.1
Primary Accession: Q99418
Other Accession: NM_017457
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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