PSD-93 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5868
Background:
The postsynaptic density protein (PSD)-93 and related membrane associated guanylate kinase (MAGUK) proteins assemble signal transduction complexes at sites of cell-cell contact including synapses. PSD-93 (also designated channel associated protein of synapse-110 or chapsyn-110) occurs only at postsynaptic sites in hippocampal neurons. PSD-95 and PSD-93 mediate ion channel clustering in heterologous cells and are believed to cluster and anchor NMDA receptors at the synapse. The glutamate receptor subunit, delta2, binds specifically to PSD-93, which is enriched in Purkinje neuron cell bodies and dendrites. In addition, PSD-93 clusters delta2 when they are coexpressed and they are colocalized at parallel fiber synapses.
Alternative Name:
Disks large homolog 2, Channel-associated protein of synapse-110, Chapsyn-110, Chapsyn110, Chapsyn 110, Postsynaptic density protein PSD-93, PSD93, DLG2
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: PSD-93 polyclonal antibody detects endogenous levels of PSD-93 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 647-692 of Human PSD-93.
MW: ~ 110 kDa
Swis Prot.: Q15700
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The postsynaptic density protein (PSD)-93 and related membrane associated guanylate kinase (MAGUK) proteins assemble signal transduction complexes at sites of cell-cell contact including synapses. PSD-93 (also designated channel associated protein of synapse-110 or chapsyn-110) occurs only at postsynaptic sites in hippocampal neurons. PSD-95 and PSD-93 mediate ion channel clustering in heterologous cells and are believed to cluster and anchor NMDA receptors at the synapse. The glutamate receptor subunit, delta2, binds specifically to PSD-93, which is enriched in Purkinje neuron cell bodies and dendrites. In addition, PSD-93 clusters delta2 when they are coexpressed and they are colocalized at parallel fiber synapses.
Alternative Name:
Disks large homolog 2, Channel-associated protein of synapse-110, Chapsyn-110, Chapsyn110, Chapsyn 110, Postsynaptic density protein PSD-93, PSD93, DLG2
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: PSD-93 polyclonal antibody detects endogenous levels of PSD-93 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 647-692 of Human PSD-93.
MW: ~ 110 kDa
Swis Prot.: Q15700
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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