PSD-95 polyclonal, anti-human, mouse, rat, bovine, monkey, zebrafish
€510.00
In stock
SKU
253206
Protein Family: GTP-binding protein, Protein Kinases, Receptors and Channels, Enzymes
Pathway and Disease: Nervous and Sensory Systems, Neurodegerative Disorders, Signaling Molecules and Interaction, Signal Transduction
Description:
PSD-95 is a molecular scaffolding protein that binds and clusters NMDA receptors at neuronal synapses. PSD-95 is involved in the guanine nucleotide-mediated signal transduction pathway. This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. PSD-95 heteromultimerizes with DLG2 and together they are recruited into the same NMDA receptor and potassium channel clusters. They may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
Alternate Names: PSD-95, Disks large homolog 4, Postsynaptic density protein 95, Synapse-associated protein 90, SAP90, DLG4, PSD95
Application Notes: E: 1:500-1:1,000; WB: 1:1,000
Accession No.: P31016
Antigen: KLH-conjugated peptide encompassing a sequence within the N-term region of rat PSD-95.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Nervous and Sensory Systems, Neurodegerative Disorders, Signaling Molecules and Interaction, Signal Transduction
Description:
PSD-95 is a molecular scaffolding protein that binds and clusters NMDA receptors at neuronal synapses. PSD-95 is involved in the guanine nucleotide-mediated signal transduction pathway. This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. PSD-95 heteromultimerizes with DLG2 and together they are recruited into the same NMDA receptor and potassium channel clusters. They may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
Alternate Names: PSD-95, Disks large homolog 4, Postsynaptic density protein 95, Synapse-associated protein 90, SAP90, DLG4, PSD95
Application Notes: E: 1:500-1:1,000; WB: 1:1,000
Accession No.: P31016
Antigen: KLH-conjugated peptide encompassing a sequence within the N-term region of rat PSD-95.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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