PSG2 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP16905b
Catalog Number: AC-AP16905b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35871
Applications: WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35871
Applications: WB
Datasheet
Request Information
Background:
The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).
Other Names:
Pregnancy-specific beta-1-glycoprotein 2, PS-beta-G-2, PSBG-2, Pregnancy-specific glycoprotein 2, Pregnancy-specific beta-1 glycoprotein E, PS-beta-E, PSG2, PSBG2
Target/Specificity:
This PSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-254 amino acids from the C-terminal region of human PSG2.
Antigen Region:
225-254
Antigen Type: Synthetic Peptide
Gene Name: PSG2
Gene ID: 5670
Primary Accession: P11465
NCBI Accession: NP_112536.2
Other Accession: NP_112536.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).
Other Names:
Pregnancy-specific beta-1-glycoprotein 2, PS-beta-G-2, PSBG-2, Pregnancy-specific glycoprotein 2, Pregnancy-specific beta-1 glycoprotein E, PS-beta-E, PSG2, PSBG2
Target/Specificity:
This PSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-254 amino acids from the C-terminal region of human PSG2.
Antigen Region:
225-254
Antigen Type: Synthetic Peptide
Gene Name: PSG2
Gene ID: 5670
Primary Accession: P11465
NCBI Accession: NP_112536.2
Other Accession: NP_112536.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review