PSG4 polyclonal (N-term), anti-human
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In stock
SKU
AC-AP19028a
Catalog Number: AC-AP19028a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39642
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39642
Applications: WB
Datasheet
Request Information
Background:
The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).
Other Names:
Pregnancy-specific beta-1-glycoprotein 4, PS-beta-G-4, PSBG-4, Pregnancy-specific glycoprotein 4, Pregnancy-specific beta-1-glycoprotein 9, PS-beta-G-9, PSBG-9, Pregnancy-specific glycoprotein 9, PSG4, CGM4, PSG9
Target/Specificity:
This PSG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-100 amino acids from the N-terminal region of human PSG4.
Antigen Region:
73-100
Antigen Type: Synthetic Peptide
Gene Name: PSG4
Gene ID: 5672
Primary Accession: Q00888
NCBI Accession: NP_002771.2;NP_998798.1
Other Accession: NP_002771.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).
Other Names:
Pregnancy-specific beta-1-glycoprotein 4, PS-beta-G-4, PSBG-4, Pregnancy-specific glycoprotein 4, Pregnancy-specific beta-1-glycoprotein 9, PS-beta-G-9, PSBG-9, Pregnancy-specific glycoprotein 9, PSG4, CGM4, PSG9
Target/Specificity:
This PSG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-100 amino acids from the N-terminal region of human PSG4.
Antigen Region:
73-100
Antigen Type: Synthetic Peptide
Gene Name: PSG4
Gene ID: 5672
Primary Accession: Q00888
NCBI Accession: NP_002771.2;NP_998798.1
Other Accession: NP_002771.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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