PSMA1 antibody (clone 1D9-1C7), anti-human
€435.00
In stock
SKU
AC-AT3453a
Catalog Number: AC-AT3453a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IF
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IF
Request Information AC-AT3453a">Request Information
Background:
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Other Names:
Proteasome subunit alpha type-1, 30 kDa prosomal protein, PROS-30, Macropain subunit C2, Multicatalytic endopeptidase complex subunit C2, Proteasome component C2, Proteasome nu chain, PSMA1, HC2, NU, PROS30, PSC2
Antigen Type:
Recombinant Protein
Gene Name: PSMA1
Gene ID: 5682
NCBI Accession: NP_002777.1;NP_683877.1
Primary Accession: P25786
Other Accession: BC002577
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Other Names:
Proteasome subunit alpha type-1, 30 kDa prosomal protein, PROS-30, Macropain subunit C2, Multicatalytic endopeptidase complex subunit C2, Proteasome component C2, Proteasome nu chain, PSMA1, HC2, NU, PROS30, PSC2
Antigen Type:
Recombinant Protein
Gene Name: PSMA1
Gene ID: 5682
NCBI Accession: NP_002777.1;NP_683877.1
Primary Accession: P25786
Other Accession: BC002577
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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