PSMA4 antibody (clone 2A10-E4), anti-human
€435.00
In stock
SKU
AC-AT3454a
Catalog Number: AC-AT3454a
Size: 100 µg
Isotype: mouse IgG2b kappa
Applications: WB, IF, E
Request Information AC-AT3454a">Request Information
Size: 100 µg
Isotype: mouse IgG2b kappa
Applications: WB, IF, E
Request Information AC-AT3454a">Request Information
Background:
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other Names:
Proteasome subunit alpha type-4, Macropain subunit C9, Multicatalytic endopeptidase complex subunit C9, Proteasome component C9, Proteasome subunit L, PSMA4, HC9, PSC9
Antigen Type:
Recombinant Protein
Gene Name: PSMA4
Gene ID: 5685
NCBI Accession: NP_001096137.1;NP_001096138.1;NP_002780.1
Primary Accession: P25789
Other Accession: BC005361
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other Names:
Proteasome subunit alpha type-4, Macropain subunit C9, Multicatalytic endopeptidase complex subunit C9, Proteasome component C9, Proteasome subunit L, PSMA4, HC9, PSC9
Antigen Type:
Recombinant Protein
Gene Name: PSMA4
Gene ID: 5685
NCBI Accession: NP_001096137.1;NP_001096138.1;NP_002780.1
Primary Accession: P25789
Other Accession: BC005361
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
|---|
Write Your Own Review