PSMA5 polyclonal (Center), anti-human

PSMA5 polyclonal (Center), anti-human

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In stock
SKU
AC-AP1449c
Catalog Number: AC-AP1449c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB12493
Applications: WB, IHC-P
Datasheet

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Background:
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PMA5 is a member of the peptidase T1A family, that is a 20S core alpha subunit.

Other Names:
Proteasome subunit alpha type-5, Macropain zeta chain, Multicatalytic endopeptidase complex zeta chain, Proteasome zeta chain, PSMA5

Target/Specificity:
This PSMA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the Central region of human PSMA5.

Antigen Region:
106-135

Antigen Type: Synthetic Peptide

Gene Name: PSMA5
Gene ID: 5686
Primary Accession: P28066
NCBI Accession: NP_001186701.1;NP_001186702.1;NP_001186703.1;NP_002781.2
Other Accession: P34064; Q9Z2U1; Q5E987
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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