PSMB11 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP11339b
Catalog Number: AC-AP11339b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB28790
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB28790
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Proteasomes generate peptides that are presented by majorhistocompatibility complex (MHC) I molecules to other cells of theimmune system. Proteolysis is conducted by 20S proteasomes,complexes of 28 subunits arranged as a cylinder in 4heteroheptameric rings: alpha-1 to -7, beta-1 to -7, beta-1 to -7,and alpha-1 to -7. The catalytic subunits are beta-1 (PSMB6; MIM600307), beta-2 (PSMB7; MIM 604030), and beta-5 (PSMB5; MIM600306). Three additional subunits, beta-1i (PSMB9; MIM 177045),beta-2i (PSMB10; MIM 176847), and beta-5i (PSMB8; MIM 177046), areinduced by gamma-interferon (IFNG; MIM 147570) and arepreferentially incorporated into proteasomes to makeimmunoproteasomes. PSMB11, or beta-5t, is a catalytic subunitexpressed exclusively in cortical thymic epithelial cells (Murataet al., 2007 [PubMed 17540904]).
Other Names:
Proteasome subunit beta type-11, Proteasome subunit beta-5t, PSMB11
Target/Specificity:
This PSMB11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-278 amino acids from the C-terminal region of human PSMB11.
Antigen Region:
250-278
Antigen Type: Synthetic Peptide
Gene Name: PSMB11
Gene ID: 122706
Primary Accession: A5LHX3
NCBI Accession: NP_001093250.1
Other Accession: NP_001093250.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Proteasomes generate peptides that are presented by majorhistocompatibility complex (MHC) I molecules to other cells of theimmune system. Proteolysis is conducted by 20S proteasomes,complexes of 28 subunits arranged as a cylinder in 4heteroheptameric rings: alpha-1 to -7, beta-1 to -7, beta-1 to -7,and alpha-1 to -7. The catalytic subunits are beta-1 (PSMB6; MIM600307), beta-2 (PSMB7; MIM 604030), and beta-5 (PSMB5; MIM600306). Three additional subunits, beta-1i (PSMB9; MIM 177045),beta-2i (PSMB10; MIM 176847), and beta-5i (PSMB8; MIM 177046), areinduced by gamma-interferon (IFNG; MIM 147570) and arepreferentially incorporated into proteasomes to makeimmunoproteasomes. PSMB11, or beta-5t, is a catalytic subunitexpressed exclusively in cortical thymic epithelial cells (Murataet al., 2007 [PubMed 17540904]).
Other Names:
Proteasome subunit beta type-11, Proteasome subunit beta-5t, PSMB11
Target/Specificity:
This PSMB11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-278 amino acids from the C-terminal region of human PSMB11.
Antigen Region:
250-278
Antigen Type: Synthetic Peptide
Gene Name: PSMB11
Gene ID: 122706
Primary Accession: A5LHX3
NCBI Accession: NP_001093250.1
Other Accession: NP_001093250.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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