PSMB4 polyclonal, anti-mouse

Background:
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.

Synonyms: 20S proteasome, 26 kDa prosomal protein, HN3, HsBPROS26, HsN3, Macropain beta chain, PROS 26, PROS26, Proteasome beta chain, Proteasome chain 3, Proteasome subunit beta type 4

Cellular Location: Nucleus Cytoplasm

Immunogen:
Recombinant protein of human PSMB4

Gene Symbol: PSMB4

Gene ID: 5692

Swiss prot: P28070

Calculated MW: 29kDa

Recommended dilution:
WB 1:8000-12000, IHC 1:100-300

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.