PSMC6 antibody (clone 2C4), anti-human, mouse, rat
€435.00
In stock
SKU
AC-AT3467a
Catalog Number: AC-AT3467a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IFhttps://www.abcepta.com/products/pdf_download/AT3467a-PSMC6-Antibody-monoclonal-M02">Request Information AC-AT3467a">Request Information
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IFhttps://www.abcepta.com/products/pdf_download/AT3467a-PSMC6-Antibody-monoclonal-M02">Request Information AC-AT3467a">Request Information
Background:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.
Other Names:
26S protease regulatory subunit 10B, 26S proteasome AAA-ATPase subunit RPT4, Proteasome 26S subunit ATPase 6, Proteasome subunit p42, PSMC6, SUG2
Antigen Type:
Recombinant Protein
Gene Name: PSMC6
Gene ID: 5706
NCBI Accession: NP_002797.3
Primary Accession: P62333
Other Accession: BC005390
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.
Other Names:
26S protease regulatory subunit 10B, 26S proteasome AAA-ATPase subunit RPT4, Proteasome 26S subunit ATPase 6, Proteasome subunit p42, PSMC6, SUG2
Antigen Type:
Recombinant Protein
Gene Name: PSMC6
Gene ID: 5706
NCBI Accession: NP_002797.3
Primary Accession: P62333
Other Accession: BC005390
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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