PSMD9 Polyclonal Antibody

Background:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene.

Research Area: Cancer, Cell Biology

Synonyms:
26S proteasome non ATPase regulatory subunit 9, 26S proteasome non-ATPase regulatory subunit 9, 26S proteasome regulatory subunit p27, Homolog of rat Bridge 1, MGC8644, p27, Proteasome (prosome macropain) 26S subunit non ATPase 9, Proteasome 26S non ATPase regulatory subunit 9, Proteasome 26S subunit non ATPase 9, PSMD 9, Psmd9, PSMD9, Rpn4

Immunogen: Recombinant protein of human PSMD9

Swissprot: O00233
Gene Accession: BC002383

Calculated MW: 25 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-10671/sc-10670/sc-292459