PSTPIP1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70899
Background:
The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
Alternative Name:
H-PIP, PAPAS, CD2BP1, PSTPIP, CD2BP1L, CD2BP1S,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: PSTPIP1 polyclonal antibody detects endogenous levels of PSTPIP1 protein.
Immunogen:
Recombinant protein of human PSTPIP1.
MW: ~ 48 kDa
Swis Prot.: O43586
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
Alternative Name:
H-PIP, PAPAS, CD2BP1, PSTPIP, CD2BP1L, CD2BP1S,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: PSTPIP1 polyclonal antibody detects endogenous levels of PSTPIP1 protein.
Immunogen:
Recombinant protein of human PSTPIP1.
MW: ~ 48 kDa
Swis Prot.: O43586
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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