PSTPIP1 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP12497a
Catalog Number: AC-AP12497a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31127
Applications: FC, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31127
Applications: FC, WB
Datasheet
Request Information
Background:
The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
Other Names:
Proline-serine-threonine phosphatase-interacting protein 1, PEST phosphatase-interacting protein 1, CD2-binding protein 1, H-PIP, PSTPIP1, CD2BP1
Target/Specificity:
This PSTPIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-118 amino acids from the N-terminal region of human PSTPIP1.
Antigen Region:
89-118
Antigen Type: Synthetic Peptide
Gene Name: PSTPIP1
Gene ID: 9051
Primary Accession: O43586
NCBI Accession: NP_003969.2
Other Accession: P97814; NP_003969.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
Other Names:
Proline-serine-threonine phosphatase-interacting protein 1, PEST phosphatase-interacting protein 1, CD2-binding protein 1, H-PIP, PSTPIP1, CD2BP1
Target/Specificity:
This PSTPIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-118 amino acids from the N-terminal region of human PSTPIP1.
Antigen Region:
89-118
Antigen Type: Synthetic Peptide
Gene Name: PSTPIP1
Gene ID: 9051
Primary Accession: O43586
NCBI Accession: NP_003969.2
Other Accession: P97814; NP_003969.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review