PTCH1 Peptide
€100.00
In stock
SKU
350500
Protein Family: Receptors and Channels
Pathway and Disease: Cancers, Development and Behavior, Signal Transduction
Alternate Names: Protein patched homolog 1; PTC; PTC1; PTCH1; PTCH
Accession No.: Q13635, NP_000255
Description:
PTCH1 is a receptor for sonic hedgehog, indian hedgehog and desert hedgehog that associates with the smoothened protein to transduce the hedgehog's protein signal. Defects in PTCH1 are the cause of several structural anomalies of the brain such as the basal cell nevus syndrome and holoprosencephaly type 7.
Format:
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 2047.2 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200138 is selected from a sequence within the C-term region of human PTCH1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C84H143N25O32S1
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Pathway and Disease: Cancers, Development and Behavior, Signal Transduction
Alternate Names: Protein patched homolog 1; PTC; PTC1; PTCH1; PTCH
Accession No.: Q13635, NP_000255
Description:
PTCH1 is a receptor for sonic hedgehog, indian hedgehog and desert hedgehog that associates with the smoothened protein to transduce the hedgehog's protein signal. Defects in PTCH1 are the cause of several structural anomalies of the brain such as the basal cell nevus syndrome and holoprosencephaly type 7.
Format:
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 2047.2 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200138 is selected from a sequence within the C-term region of human PTCH1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C84H143N25O32S1
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
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