PTEN polyclonal, anti-rat, human

Quantity: 100 µg

Background:
PTEN is also known as BZS, DEC, CWS1, GLM2, MHAM, TEP1, PTEN1. It is mapped to 10q23.3. This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. The PTEN structure reveals a phosphatase domain that is similar to protein phosphatases but also has an enlarged active site important for the accommodation of the phosphoinositide substrate.

Description:
Rabbit IgG polyclonal antibody for Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN) detection. Tested with WB in Human, Rat.

Synonyms:
10q23del antibody, Bannayan Zonana syndrome antibody, BZS antibody, DEC antibody, GLM2 antibody, ITGA 2 antibody, MGC11227 antibody, MHAM antibody, MMAC 1 antibody, MMAC1 antibody, MMAC1 phosphatase and tensin homolog deleted on chromosome 10 antibody, Multiple hamartoma (Cowden syndrome) antibody, Mutated in multiple advanced cancers 1 antibody, Mutated in Mutiple Advanced Cancers 1 antibody, Phosphatase and Tensin Homolog antibody, Phosphatase and tensin like protein antibody, Phosphatidylinositol 345 trisphosphate 3 phosphatase and dual specificity protein phosphatase PTEN antibody, Phosphatidylinositol 345 trisphosphate 3 phosphatase antibody, Phosphatidylinositol-3,4,5-trisphosphate 3 phosphatase and dual-specificity protein phosphatase PTEN antibody, Platelet antigen BR antibody, PTEN 1 antibody, Pten antibody, PTEN_HUMAN antibody, PTEN1 antibody, Tensin homolog antibody, TEP 1 antibody, TEP1 antibody, VLA 2 Receptor Alpha Subunit antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human PTEN recombinant protein (Position: E91-V403). Human PTEN shares 99.7% amino acid (aa) sequence identity with mouse PTEN.E.coli-derived human PTEN recombinant protein (Position: E91-V403). Human PTEN shares 99.7% amino acid (aa) sequence identity with mouse PTEN.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: rat.
Predicted to work with: human.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.