Ptf1a polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP2706A
Catalog Number: AC-AP2706A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB10418
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB10418
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Ptf1a is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. This protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in the Ptf1a gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.
Other Names:
Pancreas transcription factor 1 subunit alpha, Class A basic helix-loop-helix protein 29, bHLHa29, Pancreas-specific transcription factor 1a, bHLH transcription factor p48, p48 DNA-binding subunit of transcription factor PTF1, PTF1-p48, PTF1A, BHLHA29, PTF1P48
Target/Specificity:
This Ptf1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-43 amino acids from the N-terminal region of human Ptf1a.
Antigen Region:
12-43
Antigen Type: Synthetic Peptide
Gene Name: PTF1A
Gene ID: 256297
Primary Accession: Q7RTS3
NCBI Accession: NP_835455.1
Other Accession: Q64305
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Ptf1a is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. This protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in the Ptf1a gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.
Other Names:
Pancreas transcription factor 1 subunit alpha, Class A basic helix-loop-helix protein 29, bHLHa29, Pancreas-specific transcription factor 1a, bHLH transcription factor p48, p48 DNA-binding subunit of transcription factor PTF1, PTF1-p48, PTF1A, BHLHA29, PTF1P48
Target/Specificity:
This Ptf1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-43 amino acids from the N-terminal region of human Ptf1a.
Antigen Region:
12-43
Antigen Type: Synthetic Peptide
Gene Name: PTF1A
Gene ID: 256297
Primary Accession: Q7RTS3
NCBI Accession: NP_835455.1
Other Accession: Q64305
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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