PTGDR2 Polyclonal Antibody

Background:
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.PTGDR2 (Prostaglandin D2 Receptor 2) is a Protein Coding gene. Diseases associated with PTGDR2 include Folliculitis and Eosinophilic Pustular Folliculitis. Among its related pathways are Peptide ligand-binding receptors and Ibuprofen Pathway, Pharmacodynamics. GO annotations related to this gene include G-protein coupled receptor activity and prostaglandin F receptor activity. An important paralog of this gene is FPR3.

Research Area: Signal Transduction

Synonyms:
CD294, CD294 antigen, Chemoattractant receptor homologous molecule expressed on Th2 cells, chemoattractant receptor-homologous, Chemoattractant receptor-homologous molecule expressed on Th2 cells, CRTH 2, CRTH2, DL1R, DP2 prostaglandin receptor, G Protein Coupled Receptor 44, GPR 44, Gpr44, GPR44, PTGDR2, Putative G protein coupled receptor 44, Putative G-protein coupled receptor 44

Immunogen: Synthetic peptide of human PTGDR2

Swissprot: Q9Y5Y4
Gene Accession: NP004769

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.78 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.